Studies on Aminosugars. XXXII. Synthesis of 3′, 4′-Dideoxykanamycin B
نویسندگان
چکیده
منابع مشابه
Synthesis of dibekacin (3',4'-dideoxykanamycin B) from D-glucosamine and D-glucose.
(22), has been synthesized from D-glucosamine and D-glucose using an oxidative decarboxylation reaction with lead tetraacetate and a re-ductive deacetoxylation reaction with sodium borohydride as key-reactions. Using an oxidative decarboxylation reaction with lead tetraacetate and a reductive deacetoxylation reaction with sodium borohydride as key-reactions, we have been developing a versatile ...
متن کاملThe structure determination of an enzymatic inactivation product of 3',4'-dideoxykanamycin B.
Sir: As described in the preceding communi-cation1), 3' , 4/-dideoxykanamycin B (DKB) was inactivated in the presence of ATP by an enzyme preparation obtained from Es-cherichia coli JR66/W677 carrying R factor. In this communication, the structure of the inactivated antibiotic is shown to be 3', 4'-dideoxykanamycin B-2/r-adenylate by nuclear magnetic resonance study. We reported that the inacti...
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The synthesis of 6- methyl- 2- phenyl- 7H- oxazolo [3,2-b] 1,2,4-Triazine- 7-one (6, R=Ph) and its 2-P- bromophenyl analogue to the two members of a new heterocyclic system is described
متن کاملThe Sharpless asymmetric aminohydroxylation reaction: optimising ligand/substrate control of regioselectivity for the synthesis of 3- and 4-aminosugars.
An investigation of the factors responsible for the sense and magnitude of regioselectivity in the Sharpless asymmetric aminohydroxylation (AA) has been conducted. Theoretical investigations of ligand-osmium binding geometry and experimental investigations of the Sharpless AA reaction on a series of functionalized pent-2-enoic acid ester substrates demonstrate that the opposite regioselectivity...
متن کاملsynthesis of 3-aryl-2h-benzo[b]-1,4-oxazines in [omim]bf4 and reduction of organic compounds in methylimidazolium formate
در این پروژه ترکیبات 3-آریل-2h-بنزو[b]-4،1-اکسازین ها از مواد اولیه تجاری مشتقات دو آمینو فنول و ?-هالو کتون های آروماتیک در مایع یونی 1-اکتیل-3-متیل ایمیدازولیوم تترا فلورو بورات([omim]bf4) سنتز شده است. این واکنش توسط باز پتاسیم کربنات محلول از طریق o-آلکیلاسیون و سپس یک واکنش آمیداسیون درون مولکولی خود بخود در مدت زمان کوتاه انجام می شود. ترکیبات 4،1-بنزوکسازین به این روش با بهره خوب تا آلی ...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1972
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.45.3624